CORTICAL DYNAMICS of spontaneous activity

 
 

We use a combination of two-photon imaging, whole cell recordings, real-time control, and computational modeling to characterize how the functional connectivity of neural networks leads to emergent network behavior in neocortex. 

Relevant Publications

Fernandez FR, Noueihed J, White JA (2019) Voltage-Dependent Membrane Properties Shape the Size But Not the Frequency Content of Spontaneous Voltage Fluctuations in Layer 2/3 Somatosensory Cortex. J. Neuroscience, 39(12):2221-2237.

Fernandez FR, Rahsepar B, and White JA (2018) Differences in the Electrophysiological Properties of Mouse Somatosensory Layer 2/3 Neurons In Vivo and Slice Stem from Intrinsic Sources Rather than a Network-Generated High Conductance State. eNeuro. 2018 Apr 13;5(2). pii: ENEURO.0447-17.2018.